aromatase enzyme estrogen systhesis



Die Aromatase (auch CYP19A1) ist das Enzym, das in Wirbeltieren die Umsetzung von Testosteron zu Estradiol bzw. von Androstendion zu Estron katalysiert. Diese Aromatisierung von Androgenen ist der entscheidende letzte Schritt bei der Biosynthese der Estrogene. Aromatase, auch Estrogen-Synthase genannt, ist eine
Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1, a member of the cytochrome P450 superfamily (EC 1.14.14.1), which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular
J Steroid Biochem Mol Biol. 1997 Apr;61(3-6):267-71. Estrogen production via the aromatase enzyme in breast carcinoma: which cell type is responsible? Santen RJ(1), Santner SJ, Pauley RJ, Tait L, Kaseta J, Demers LM, Hamilton C, Yue W, Wang JP. Author information: (1)Department of Internal Medicine, University of
Neurosci Lett. 2004 Sep 30;368(3):279-84. Aromatase, the enzyme responsible for estrogen biosynthesis, is expressed by human and rat glioblastomas. Yague JG(1), Lavaque E, Carretero J, Azcoitia I, Garcia-Segura LM. Author information: (1)Instituto Cajal, C.S.I.C., Avenida Doctor Arce 37, E-28002 Madrid, Spain.
Aromatase is the enzyme responsible for the conversion of androgens to estrogen in many tissues, including the gonads and adipocytes. Increased .... In some cases an inversion results in a constituitively active cryptic promoter placed in control of the CYP19A1 gene, driving excess aromatase production. Inappropriate
30.09.2004 -
INTRODUCTION. Estrogen biosynthesis from C19 steroids is catalyzed by the enzyme aromatase cytochrome P450 (1). In humans, aromatase is expressed in both the granulosa and luteal cells of the ovary, and also in various extra-glandular sites including the placenta, brain, bone, testis and adipose tissue (2). Aromatase
See figure: 'The estrogen synthesis enzyme aromatase is responsible for the sexually dimorphic effects of...' from publication 'Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition' on ResearchGate, the professional network for scientists.
17.11.2015 -

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